Developing BOLD New Antibody

Treatments for
Cancer and Autoimmune Diseases

Alanis Therapeutics, a spin out of the San Diego antibody engineering company AvantGen, is harnessing the potential of antibody-based therapeutics to target novel pathways and develop new agents to treat cancer and autoimmunity. Our lead product, ATI-D1, is an antibody that inhibits notch1 signaling between osteoblasts and leukemic stem cells-a key oncogenic driver of tumor progression in MDS/AML.